Tennessee @ San Francisco
Tennessee +12½ -110 over San Francisco

Posted at 9:00 AM ET. Odds are subject to change

Tennessee +12.5 over San Francisco

4:25 PM ET. This number feels heavy for a Titans team that finally showed some pulse last week. Tennessee snapped a seven-game skid in Cleveland by leaning on the run game, protecting Cam Ward from having to do too much, and playing physical football for most of the afternoon. Ward wasn’t spectacular, but that’s not the point. This offense doesn’t need him to trade punches with Brock Purdy — it needs him to avoid disaster while the ground game and defense shorten the contest. As ugly as Tennessee’s record looks, they’ve quietly shifted into a low-variance profile that plays much better catching nearly two touchdowns than trying to win outright.

San Francisco deserves to be favored, but the market is pricing them closer to a blowout machine than a team that has leaned heavily on defense and clock control during this recent stretch. The 49ers have been excellent at limiting points, not necessarily running teams off the field, and that matters when you’re laying double digits. Tennessee’s best path here is obvious: slow the tempo, live with punts, and force San Francisco to sustain long drives without short fields. If the Titans can avoid late-game giveaways — the exact thing that burned them in Cleveland — this has all the makings of a grind-it-out game that stays inside the number. We’re not asking Tennessee to be good, just stubborn.

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Our Pick

Tennessee +12½ -110 (Risking 2.20 units - To Win: 2.00)