Bookmaker   +16½ -110

Posted at 8:00 AM ET. Odds are subject to change

South Dakota +16½ over Iowa St

Jack Trice Stadium – Ames, IA

3:30 PM ET. Iowa State’s win over Kansas State in Dublin looks impressive, but the game itself was riddled with variance. The Cyclones benefited from breaks rather than outright dominance. Now they return home with the annual Cy-Hawk game looming next week, creating a sandwich spot with letdown and lookahead written all over it.

South Dakota is not a pushover. The Coyotes are ranked #5 in the FCS and play disciplined, championship-caliber football at their level. They will view this as an opportunity to make a statement. Historically, Week One always delivers an FCS-over-FBS upset candidate, and this matchup fits the mold. Overlay.

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